SCHEMBL17922792

SCHEMBL17922792

N[C@@H](CCCCNC(=O)CCCNC(=O)CCCCCCCCCCCCCCCS(=O)(=O)O)C(=O)NCCCC[C@H](N)C(=O)NCCOCCOCC(=O)NCCOCCO

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.46
▸ TLR2 O60603 4/20 0.38
▸ GNAI3 P08754 1/20 0.37
▸ GNAO1 P09471 1/20 0.37
▸ GNAI1 P63096 1/20 0.37
▸ DPP7 Q9UHL4 1/20 0.35
▸ CA2 P00918 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34
▸ RRM1 P23921 1/20 0.33
▸ CD40 P25942 1/20 0.33
▸ EPOR P19235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17922787 0.93 GLP1R (0.42) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493177 0.88 GLP1R (0.53) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493061 0.87 GLP1R (0.48) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493178 0.87 GLP1R (0.48) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493059 0.87 GLP1R (0.48) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493106 0.86 GLP1R (0.56) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL17922793 0.86 GLP1R (0.47) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493162 0.86 GLP1R (0.47) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493127 0.85 GLP1R (0.56) GLP1RTLR2GNAI3GNAO1GNAI1
SCHEMBL16493168 0.82 GNAI3 (0.41) GLP1RTLR2GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof NOVO NORDISK A/S (DK) 2016-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200791-A1 GLP-1 Derivatives, and Uses Thereof GLP1R, IAPP, GCG GLP1R 1/4885TLR2 2716/4885GNAI3 1890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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