Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | CD40 | P25942 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493059 | 1.00 | GLP1R (0.48) | GLP1RGNAI3GNAO1GNAI1FNTA | |
| SCHEMBL16493061 | 1.00 | GLP1R (0.48) | GLP1RGNAI3GNAO1GNAI1FNTA | |
| SCHEMBL16493168 | 0.94 | GNAI3 (0.41) | GLP1RGNAI3GNAO1GNAI1FNTA | |
| SCHEMBL16493064 | 0.93 | GLP1R (0.45) | GLP1RGNAI3GNAO1GNAI1FNTA | |
| SCHEMBL17922790 | 0.91 | GLP1R (0.58) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL16493177 | 0.91 | GLP1R (0.53) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL17922792 | 0.87 | GLP1R (0.46) | GLP1RGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL17922797 | 0.86 | GLP1R (0.48) | GLP1RGNAI3GNAO1GNAI1FNTA | |
| SCHEMBL17922807 | 0.86 | GLP1R (0.47) | GLP1RGNAI3GNAO1GNAI1FNTA | |
| SCHEMBL17922789 | 0.83 | GLP1R (0.54) | GLP1RGNAI3GNAO1GNAI1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022400-A1 | GLP-1 DERIVATIVES, AND USES THEREOF | NOVO NORDISK A/S (DK) | 2015-02-19 | — | — | WO | disclosed |