SCHEMBL1649381

SCHEMBL1649381

O=C(O)C(=Cc1ccccc1)C(=O)c1ccccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
TP53 P04637 1/20 0.50
BCHE P06276 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.49
KDM4E B2RXH2 5/20 0.48
HPGD P15428 5/20 0.48
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MAOB P27338 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4050625 1.00 MAPT (0.50) MAPTTP53BCHECYP2C19HTT
SCHEMBL7616184 0.84 ALDH1A1 (0.52) MAPTTP53HTTKDM4EHPGD
SCHEMBL1073512 0.83 MAPT (0.55) MAPTTP53BCHECYP2C19HTT
SCHEMBL4051210 0.80 MEN1 (0.45) MAPTTP53HTTKDM4EALDH1A1
SCHEMBL4051205 0.80 MEN1 (0.45) MAPTTP53HTTKDM4EALDH1A1
SCHEMBL4049087 0.79 ALDH1A1 (0.42) MAPTBCHEHTTKDM4EHPGD
SCHEMBL4049090 0.79 ALDH1A1 (0.42) MAPTBCHEHTTKDM4EHPGD
SCHEMBL1887493 0.79 MEN1 (0.48) MAPTBCHECYP2C19HTTKDM4E
SCHEMBL1887498 0.79 MEN1 (0.48) MAPTBCHECYP2C19HTTKDM4E
SCHEMBL1887496 0.79 MEN1 (0.48) MAPTBCHECYP2C19HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4144416-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER Johnson & Johnson Consumer Inc. (US) 2023-03-08 EP claimed
EP-3349863-B1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2022-01-19 EP claimed
CN-108025197-B Foaming sunscreen compositions containing UV radiation absorbing compounds and superhydrophilic amphiphilic copolymers 强生消费者公司 2021-09-07 CN claimed
CN-108112232-B Sunscreen compositions comprising superhydrophilic amphiphilic copolymers 强生消费者公司 2021-08-10 CN claimed
CN-111454445-A Ultraviolet radiation absorbing polyethers 强生消费者公司 2020-07-28 CN claimed
EP-3349863-A1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER Johnson & Johnson Consumer Inc. (US) 2018-07-25 EP claimed
EP-3349723-A1 SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS Johnson & Johnson Consumer Inc. (US) 2018-07-25 EP claimed
EP-2679616-B1 Ultraviolet radiation absorbing polyethers JOHNSON & JOHNSON CONSUMER INC (US) 2018-05-16 EP claimed
EP-2866898-B1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER INC (US) 2018-04-04 EP claimed
EP-2866783-B1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2018-01-10 EP claimed
WO-2014004176-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO claimed
WO-2014004477-A2 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-03 WO claimed
US-20140004064-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER KENVUE BRANDS LLC 2014-01-02 US claimed
US-20140004063-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US claimed
US-20140004060-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US claimed
US-20140004061-A1 ULTRAVIOLET RADIATION ABSORBING POLYETHERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-01-02 US claimed
US-8475774-B2 Sunscreen compositions comprising an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-07-02 US claimed
EP-2533860-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER Johnson & Johnson Consumer Companies Inc. (US) 2012-12-19 EP claimed
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC. 2011-08-11 US claimed
WO-2011097555-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER COMPANIES INC. (US) 2011-08-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER ERCC1, MMS19, ERCC5 MAPT 380/4885TP53 46/4885BCHE 4108/4885
US-20140004061-A1 ULTRAVIOLET RADIATION ABSORBING POLYETHERS ERCC4, XRCC6, PUF60 MAPT 98/4885TP53 1153/4885BCHE 4521/4885
US-20140004060-A1 ULTRAVIOLET RADIATION ABSORBING POLYMERS PARG, PARN, PUF60 MAPT 106/4885TP53 1556/4885BCHE 4465/4885
US-20140004064-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER PCNA, SUN2, TTPA MAPT 1108/4885TP53 102/4885BCHE 3960/4885
US-20140004063-A1 SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER MMS19, SUN2, ERCC1 MAPT 209/4885TP53 87/4885BCHE 3746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.