Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494430 | 0.87 | SMN1; SMN2 (0.51) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16494235 | 0.84 | ACHE (0.52) | MAPTALDH1A1MEN1KMT2AACHE | |
| SCHEMBL16494019 | 0.84 | BCHE (0.58) | ALDH1A1MEN1KMT2AACHEBCHE | |
| SCHEMBL16494918 | 0.84 | MEN1 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16494103 | 0.81 | SMN1; SMN2 (0.46) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16494333 | 0.79 | ACHE (0.49) | MAPTALDH1A1KDM4EACHEBCHE | |
| SCHEMBL29868178 | 0.78 | PLAU (0.45) | MAPTKDM4EKMT2AACHEBCHE | |
| SCHEMBL2403731 | 0.78 | PLAU (0.45) | MAPTKDM4EKMT2AACHEBCHE | |
| SCHEMBL16494147 | 0.75 | ACHE (0.51) | MAPTALDH1A1ACHEBCHESMN1; SMN2 | |
| SCHEMBL846894 | 0.75 | NPC1 (0.46) | MAPTALDH1A1KDM4ETP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394990-A1 | INDOLINE DERIVATIVES | Kyoto University (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110294850-A1 | INDOLINE DERIVATIVES | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294850-A1 | INDOLINE DERIVATIVES | BCHE, ACHE, INMT | MAPT 2067/4885ALDH1A1 392/4885KDM4E 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.