Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 2/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494867 | 1.00 | PTK2 (0.40) | PTK2PTK2BCCNT1CDK9ABL1 | |
| SCHEMBL16495191 | 0.93 | PTK2 (0.40) | PTK2PTK2BCCNT1CDK9ABL1 | |
| SCHEMBL16494581 | 0.93 | PTK2 (0.40) | PTK2PTK2BCCNT1CDK9ABL1 | |
| SCHEMBL16495061 | 0.92 | PTK2 (0.46) | PTK2PTK2BCCNT1CDK9ABL1 | |
| SCHEMBL16494444 | 0.92 | PTK2 (0.46) | PTK2PTK2BCCNT1CDK9ABL1 | |
| SCHEMBL16494497 | 0.85 | PTK2 (0.45) | PTK2PTK2BABL1BCL6PAK4 | |
| SCHEMBL2598604 | 0.85 | PTK2 (0.45) | PTK2PTK2BABL1BCL6PAK4 | |
| SCHEMBL12185474 | 0.85 | CCNT1 (0.46) | CCNT1CDK9ABL1PAK4PAK1 | |
| SCHEMBL16494405 | 0.81 | JAK2 (0.48) | PTK2PTK2BCCNT1CDK9ABL1 | |
| SCHEMBL12185447 | 0.81 | PAK1 (0.44) | CCNT1CDK9ABL1PAK4PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |