Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494929 | 0.94 | GABRA1 (0.56) | GABRA1GABRA2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL16495327 | 0.90 | GABRA1 (0.59) | GABRA1GABRA2L3MBTL1LMNAADORA3 | |
| SCHEMBL16495207 | 0.86 | GABRA1 (0.53) | GABRA1GABRA2ALDH1A1ADORA3MPO | |
| SCHEMBL16494482 | 0.81 | GABRA1 (0.56) | GABRA1GABRA2ALDH1A1LMNAADORA3 | |
| SCHEMBL16495511 | 0.77 | GABRA1 (0.67) | GABRA1GABRA2ALDH1A1LMNATLR7 | |
| SCHEMBL3650747 | 0.69 | GABRA1 (0.52) | GABRA1GABRA2ALDH1A1ADORA3TLR7 | |
| SCHEMBL19583344 | 0.67 | POLB (0.55) | ALDH1A1L3MBTL1LMNANPY1RNPY2R | |
| SCHEMBL16495243 | 0.65 | GABRA1 (0.44) | GABRA1GABRA2ALDH1A1L3MBTL1ADORA3 | |
| SCHEMBL16974026 | 0.65 | TLR7 (0.54) | ADORA3MPOTLR7PDE4APDE4B | |
| SCHEMBL7283175 | 0.65 | MAPT (0.51) | ALDH1A1L3MBTL1LMNANPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294799-A1 | Organic Compounds | NOVARTIS AG | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294799-A1 | Organic Compounds | SLCO4C1, SLCO1B1, SLCO1B3 | GABRA1 446/4885GABRA2 654/4885ALDH1A1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.