Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494460 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TSHRL3MBTL1 | |
| SCHEMBL16495327 | 0.69 | GABRA1 (0.59) | GABRA1GABRA2TLR7ADORA3L3MBTL1 | |
| SCHEMBL3650858 | 0.68 | GABRA1 (0.52) | GABRA1GABRA2TLR7ADORA3TP53 | |
| SCHEMBL16494929 | 0.66 | GABRA1 (0.56) | GABRA1GABRA2TLR7ALDH1A1CYP1A2 | |
| SCHEMBL16494366 | 0.65 | GABRA1 (0.55) | GABRA1GABRA2TLR7ALDH1A1CYP1A2 | |
| SCHEMBL30310865 | 0.62 | PDE5A (0.48) | GABRA1GABRA2PDE5ACLK4ALDH1A1 | |
| SCHEMBL16494482 | 0.62 | GABRA1 (0.56) | GABRA1GABRA2TLR7ALDH1A1CYP1A2 | |
| SCHEMBL4758349 | 0.61 | PDE5A (0.46) | PDE5ACLK4ALDH1A1CYP1A2TSHR | |
| SCHEMBL27914444 | 0.60 | PDE5A (0.56) | PDE5ACLK4ALDH1A1TP53HRH4 | |
| SCHEMBL9431635 | 0.60 | PLAU (0.50) | PDE5ACLK4L3MBTL1ELANECHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294799-A1 | Organic Compounds | NOVARTIS AG | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294799-A1 | Organic Compounds | SLCO4C1, SLCO1B1, SLCO1B3 | GABRA1 446/4885GABRA2 654/4885PDE5A 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.