Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046155 | 0.91 | GAA (0.54) | MAPTTP53PARP1ALDH1A1TOP2A | |
| SCHEMBL10135252 | 0.83 | PARP1 (0.70) | MAPTPARP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL19583344 | 0.79 | POLB (0.55) | MAPTPARP1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9819484 | 0.78 | L3MBTL1 (0.48) | MAPTALDH1A1LMNAL3MBTL1NPY1R | |
| SCHEMBL28002627 | 0.77 | TLR8 (0.54) | MAPTTP53ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL14027310 | 0.76 | GPR3 (0.44) | MAPTPARP1ALDH1A1L3MBTL1TOP2A | |
| SCHEMBL15561024 | 0.75 | GAA (0.62) | MAPTTP53ALDH1A1L3MBTL1GAA | |
| SCHEMBL28473290 | 0.74 | SOAT1 (0.55) | MAPTTP53ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7048658 | 0.74 | CYP1A2 (0.58) | MAPTALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL4270796 | 0.73 | LMNA (0.56) | MAPTTP53ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457243-A1 | Novel tricyclic compounds | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |