Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | DHODH | Q02127 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372455 | 0.86 | ATM (0.55) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL29412847 | 0.80 | DHODH (0.59) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL25342600 | 0.80 | DHODH (0.59) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL1375701 | 0.79 | RAB9A (0.49) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL1375914 | 0.78 | TUBB4A (0.48) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL10094259 | 0.76 | TDP1 (0.49) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL2047264 | 0.76 | DHODH (0.70) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL15636368 | 0.76 | DHODH (0.72) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL479877 | 0.76 | DHODH (1.00) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL10640763 | 0.75 | SMN1; SMN2 (0.67) | RAB9AMEN1KMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |