Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495321 | 0.93 | BCHE (0.52) | BCHEACHE | |
| SCHEMBL16495116 | 0.93 | BCHE (0.52) | BCHEACHE | |
| SCHEMBL16494341 | 0.92 | ACHE (0.62) | BCHEACHE | |
| SCHEMBL16494198 | 0.91 | TNF (0.54) | BCHEACHE | |
| SCHEMBL16494977 | 0.91 | BCHE (0.50) | BCHEACHE | |
| SCHEMBL16494439 | 0.91 | ACHE (0.56) | BCHEACHE | |
| SCHEMBL16494777 | 0.91 | ACHE (0.51) | BCHEACHE | |
| SCHEMBL16494744 | 0.90 | BCHE (0.51) | BCHEACHE | |
| SCHEMBL16494781 | 0.90 | ACHE (0.51) | BCHEACHE | |
| SCHEMBL16494948 | 0.90 | ALOX5 (0.53) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394990-A1 | INDOLINE DERIVATIVES | Kyoto University (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110294850-A1 | INDOLINE DERIVATIVES | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294850-A1 | INDOLINE DERIVATIVES | BCHE, ACHE, INMT | BCHE 1/4885ACHE 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.