Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709284 | 0.77 | — | — | |
| SCHEMBL12494483 | 0.77 | CYP2C19 (0.39) | TSHRCYP2C19 | |
| SCHEMBL19346720 | 0.72 | — | — | |
| SCHEMBL27590444 | 0.70 | ALDH1A1 (0.33) | TSHRCYP2C19 | |
| SCHEMBL28750893 | 0.70 | ALDH1A1 (0.33) | TSHRCYP2C19 | |
| SCHEMBL12870314 | 0.70 | ALDH1A1 (0.33) | TSHRCYP2C19 | |
| SCHEMBL27608813 | 0.70 | ALDH1A1 (0.33) | TSHRCYP2C19 | |
| SCHEMBL28665742 | 0.69 | POLB (0.42) | TSHRCYP2C19 | |
| SCHEMBL9753105 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL5342543 | 0.67 | CHRNB2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |