Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 2/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641213 | 0.76 | TSHR (0.31) | TSHRLPO | |
| SCHEMBL30491883 | 0.74 | — | — | |
| SCHEMBL5344293 | 0.73 | MAPK1 (0.38) | TSHRLPOP2RX4ALDH1A1 | |
| SCHEMBL28289735 | 0.73 | BCHE (0.33) | TSHRLPOP2RX4BCHE | |
| SCHEMBL28299411 | 0.73 | CHRNB2 (0.32) | TSHRLPOP2RX4 | |
| SCHEMBL4256336 | 0.70 | P2RX4 (0.33) | P2RX4 | |
| SCHEMBL1649446 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL5773612 | 0.62 | USP2 (0.38) | BCHE | |
| SCHEMBL6602093 | 0.61 | P2RX4 (0.32) | TSHRP2RX4 | |
| SCHEMBL568621 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | claimed |
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |