Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599419 | 0.92 | MTNR1A (0.43) | MTNR1AMTNR1BCSF1RNTRK2HTR2A | |
| SCHEMBL2598572 | 0.90 | HTR2A (0.44) | MTNR1AMTNR1BHTR2AHTR1ADRD2 | |
| SCHEMBL14840253 | 0.89 | HTR2A (0.50) | MTNR1AMTNR1BHTR2AUSP2CYP1A2 | |
| SCHEMBL16494517 | 0.87 | MTNR1A (0.43) | MTNR1AMTNR1BCSF1RNTRK2HTR2A | |
| SCHEMBL2598664 | 0.86 | IP6K1 (0.47) | MTNR1AMTNR1BHTR2AHTR6USP2 | |
| SCHEMBL14839743 | 0.83 | HTR2A (0.49) | MTNR1AMTNR1BHTR2AUSP2CYP1A2 | |
| SCHEMBL2598634 | 0.83 | HTR2A (0.41) | HTR2AHTR1ADHFRUSP2CYP1A2 | |
| SCHEMBL2598830 | 0.82 | HTR1A (0.42) | MTNR1AMTNR1BHTR2AHTR1AUSP2 | |
| SCHEMBL2598769 | 0.82 | HTR2A (0.43) | MTNR1AMTNR1BHTR2AHTR1ADRD2 | |
| SCHEMBL16494583 | 0.81 | LMNA (0.43) | HTR2AHTR1AUSP2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |