Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494769 | 0.83 | CYP1A2 (0.34) | BRD4CYP1A2HIF1A | |
| SCHEMBL22207271 | 0.83 | MAPT (0.37) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16494534 | 0.79 | BRD4 (0.44) | BRD4CYP1A2HIF1AALDH1A1MMP2 | |
| SCHEMBL7022793 | 0.73 | BRD4 (0.37) | BRD4CYP1A2HIF1AL3MBTL1MAPT | |
| SCHEMBL10818686 | 0.72 | BRD4 (0.39) | BRD4CYP1A2HIF1AL3MBTL1MAPT | |
| SCHEMBL2597463 | 0.71 | BRD4 (0.45) | BRD4CYP1A2HIF1ACYP2C19ALDH1A1 | |
| SCHEMBL4475842 | 0.71 | BRD4 (0.35) | BRD4CYP1A2HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8394065 | 0.70 | FKBP1A (0.36) | BRD4CYP1A2HIF1A | |
| SCHEMBL6893472 | 0.69 | L3MBTL1 (0.39) | L3MBTL1MAPT | |
| SCHEMBL18556394 | 0.69 | L3MBTL1 (0.39) | L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |