Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495343 | 0.90 | ACHE (0.45) | ACHETNF | |
| SCHEMBL16494800 | 0.82 | ACHE (0.38) | ACHETNF | |
| SCHEMBL16495267 | 0.80 | MAPT (0.47) | TNF | |
| SCHEMBL16495163 | 0.78 | TNF (0.43) | ACHETNF | |
| SCHEMBL16495220 | 0.75 | MAPT (0.46) | ACHETNF | |
| SCHEMBL16494753 | 0.75 | CAPN1 (0.42) | ACHETNF | |
| Methane SCHEMBL27429811 | 0.75 | TNF (0.46) | ACHETNF | |
| SCHEMBL16495164 | 0.74 | HDAC1 (0.44) | ACHETNF | |
| SCHEMBL27429810 | 0.74 | TNF (0.45) | ACHETNF | |
| SCHEMBL16495305 | 0.74 | TNF (0.48) | ACHETNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294850-A1 | INDOLINE DERIVATIVES | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294850-A1 | INDOLINE DERIVATIVES | BCHE, ACHE, INMT | ACHE 2/4885TNF 4863/4885PKM 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.