Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 4/20 | 0.44 |
| ▸ | HTR1B | P28222 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494785 | 0.91 | HTR2C (0.42) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL16494541 | 0.89 | HTR1A (0.52) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL16494650 | 0.88 | HTR1A (0.39) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL16494871 | 0.88 | HTR1A (0.42) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL16494258 | 0.87 | HTR1A (0.41) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL16495045 | 0.87 | HTR1A (0.40) | HTR1AHTR2CHTR2A | |
| SCHEMBL2598672 | 0.84 | MC5R (0.46) | HTR1AHTR2A | |
| SCHEMBL16495336 | 0.84 | HTR6 (0.43) | HTR1AHTR2A | |
| SCHEMBL14839993 | 0.84 | HTR2A (0.42) | HTR1AHTR2CHTR1DHTR1BHTR2A | |
| SCHEMBL14839726 | 0.84 | MPO (0.47) | HTR1AHTR2ATRPM8MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2395001-A1 | Novel pyrimidine derivatives | Chemilia AB (SE) | 2011-12-14 | — | — | EP | disclosed |