Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055360 | 0.79 | LMNA (0.51) | RAB9ATSHRALDH1A1KDM4EPIN1 | |
| SCHEMBL11891663 | 0.73 | LMNA (0.48) | RAB9ATSHRALDH1A1KDM4EPIN1 | |
| SCHEMBL1054878 | 0.73 | LMNA (0.48) | RAB9ATSHRALDH1A1KDM4EPIN1 | |
| SCHEMBL11891662 | 0.73 | LMNA (0.48) | RAB9ATSHRALDH1A1KDM4EPIN1 | |
| SCHEMBL3376310 | 0.72 | ALDH1A1 (0.49) | RAB9ATSHRALDH1A1KDM4EPIN1 | |
| SCHEMBL13417273 | 0.71 | LMNA (0.55) | RAB9ATSHRALDH1A1KDM4EGSK3A | |
| SCHEMBL3372555 | 0.71 | LMNA (0.53) | RAB9ATSHRALDH1A1KDM4EGSK3A | |
| SCHEMBL16495110 | 0.71 | ALDH1A1 (0.36) | RAB9ATSHRALDH1A1KDM4EPIN1 | |
| SCHEMBL13417154 | 0.70 | LMNA (0.52) | RAB9ATSHRALDH1A1KDM4EGSK3A | |
| SCHEMBL16507769 | 0.70 | RAB9A (0.43) | RAB9ATSHRALDH1A1KDM4EPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |