SCHEMBL16495684

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16495846	0.90	MAPK8 (0.55)	HPGDSNPC1PRKACAPRKXPRKCQ
	SCHEMBL16496284	0.90	CA2 (0.56)	HPGDSNPC1PRKACAPRKXPRKCQ
	SCHEMBL16495431	0.88	HPGDS (0.61)	HPGDSNPC1PRKACAPRKXPRKCQ
	SCHEMBL16495484	0.87	HPGDS (0.56)	HPGDSMAPTNAMPTALDH1A1MEN1
	SCHEMBL16496139	0.87	RORC (0.47)	HPGDSMAPTNAMPTSTAMBPCOPS5
	SCHEMBL16496112	0.87	HPGDS (0.56)	HPGDSMAPTNAMPTMEN1KMT2A
	SCHEMBL16495980	0.86	HPGDS (0.59)	HPGDSNPC1PRKACAPRKXPRKCQ
	SCHEMBL16495728	0.86	HPGDS (0.59)	HPGDSNPC1PRKACAPRKXPRKCQ
	SCHEMBL16496373	0.86	HPGDS (0.72)	HPGDSNPC1PRKACAPRKXPRKCQ
	SCHEMBL16496440	0.86	HPGDS (0.72)	HPGDSNAMPTALDH1A1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.