SCHEMBL1649638

SCHEMBL1649638

O=S(=O)(O)c1cc(I)c(O)c(I)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ING2 Q9H160 1/20 0.52
TTR P02766 2/20 0.48
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
NSD2 O96028 3/20 0.41
CASP6 P55212 2/20 0.41
GAA P10253 1/20 0.41
PLCG1 P19174 1/20 0.41
DNMT1 P26358 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NT5E P21589 3/20 0.39
ALB P02768 1/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 3/20 0.39
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8180623 0.88 ING2 (0.42) ING2TTRLCKFYNLMNA
SCHEMBL15671336 0.87 ING2 (0.45) ING2TTRLCKFYNLMNA
SCHEMBL22396641 0.83 LCK (0.41) ING2LCKFYNLMNANSD2
SCHEMBL3140050 0.82 LCK (0.44) ING2LCKFYNLMNANSD2
SCHEMBL16651363 0.80 TTR (0.48) TTRLMNAMEN1HTTKMT2A
SCHEMBL1650498 0.76 DUSP5 (0.55) TTRLMNAMEN1HTTKMT2A
SCHEMBL4730286 0.76 CA1 (0.61) ING2LCKFYNLMNANSD2
SCHEMBL10719866 0.75 ING2 (0.52) ING2LCKFYNLMNAMEN1
SCHEMBL2298316 0.75 ALDH1A1 (0.59) LMNANSD2CASP6GAANT5E
SCHEMBL219222 0.74 LCK (0.57) ING2LCKFYNLMNANSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10600524-B2 Radiation protection device and methods thereof STEMRAD LTD. (IL) 2020-03-24 US claimed
EP-2706881-B1 RADIATION PROTECTION DEVICE AND METHODS THEREOF STEMRAD LTD (IL) 2018-07-25 EP claimed
US-20180174696-A9 RADIATION PROTECTION DEVICE AND METHODS THEREOF STEMRAD LTD. (IL) 2018-06-21 US claimed
EP-1547096-B1 MULTIPLE HAZARD PROTECTION ARTICLES AND METHODS FOR MAKING THEM MERIDIAN RES AND DEVELOPMENT (US) 2018-04-11 EP claimed
US-20150004131-A1 RADIATION PROTECTION DEVICE AND METHODS THEREOF MILSTEIN OREN (IL) 2015-01-01 US claimed
EP-2706881-A2 RADIATION PROTECTION DEVICE AND METHODS THEREOF Stemrad Ltd. (IL) 2014-03-19 EP claimed
CN-101385091-B Radiation protective article of clothing MERIDIAN RES & DEV 2012-12-26 CN claimed
WO-2012154962-A2 RADIATION PROTECTION DEVICE AND METHODS THEREOF STEMRAD LTD. (IL) 2012-11-15 WO claimed
CN-1689120-B Multiple hazard prevention article and method of making same MERIDIAN RES & DEV 2012-05-09 CN claimed
US-20090114857-A1 RADIATION DETECTABLE AND PROTECTIVE ARTICLES MERIDIAN RESEARCH AND DEVELOPMENT (US) 2009-05-07 US claimed
US-6841791-B2 Multiple hazard protection articles and methods for making them MERIDIAN RESEARCH AND DEVELOPMENT (US) 2005-01-11 US claimed
US-6828578-B2 Lightweight radiation protective articles and methods for making them MERIDIAN RESEARCH AND DEVELOPMENT 2004-12-07 US claimed
WO-2004021811-A2 MULTIPLE HAZARD PROTECTION ARTICLES AND METHODS FOR MAKING THEM MERIDIAN RESEARCH AND DEVELOPMENT (US) 2004-03-18 WO claimed
US-20040004196-A1 Multiple hazard protection articles and methods for making them MERIDIAN RESEARCH AND DEVELOPMENT 2004-01-08 US claimed
US-20030010939-A1 Lightweight radiation protective articles and methods for making them MERIDIAN RESEARCH AND DEVELOPMENT 2003-01-16 US claimed
US-6459091-B1 Lightweight radiation protective garments MERIDIAN RESEARCH AND DEVELOPMENT 2002-10-01 US claimed
US-20020043631-A1 Lightweight radiation protective garments MERIDIAN RESEARCH AND DEVELOPMENT 2002-04-18 US claimed
EP-1141973-A1 LIGHTWEIGHT RADIATION PROTECTIVE GARMENTS Meridian Research and Development (US) 2001-10-10 EP claimed
US-6281515-B1 Lightweight radiation protective garments MERIDIAN RESEARCH AND DEVELOPMENT 2001-08-28 US claimed
WO-2000034957-A1 LIGHTWEIGHT RADIATION PROTECTIVE GARMENTS MERIDIAN RESEARCH AND DEVELOPMENT (US) 2000-06-15 WO claimed