Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.61 |
| ▸ | CA2 | P00918 | 7/20 | 0.61 |
| ▸ | CA9 | Q16790 | 7/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NT5E | P21589 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140050 | 0.78 | LCK (0.44) | CA1CA2CA9CA3ALDH1A1 | |
| SCHEMBL1649638 | 0.76 | ING2 (0.52) | CA1CA2CA9ALDH1A1NT5E | |
| SCHEMBL22396641 | 0.74 | LCK (0.41) | CA1CA2CA9ALDH1A1NT5E | |
| SCHEMBL9220939 | 0.74 | LCK (0.55) | CA1CA2ALDH1A1NT5ETSHR | |
| SCHEMBL10064648 | 0.74 | CA1 (0.68) | CA1CA2CA9ALDH1A1NT5E | |
| SCHEMBL21589346 | 0.73 | ALDH1A1 (0.56) | CA1CA2CA9CA3ALDH1A1 | |
| Potassium Ion SCHEMBL4730283 | 0.73 | CA2 (0.61) | CA1CA2CA9CA3TDP1 | |
| SCHEMBL156895 | 0.71 | CYP2C19 (0.50) | ALDH1A1NT5ETSHRHSD17B10TDP1 | |
| SCHEMBL17262657 | 0.71 | ALDH1A1 (0.50) | CA1CA2CA9ALDH1A1NT5E | |
| SCHEMBL219222 | 0.71 | LCK (0.57) | CA1CA2ALDH1A1NT5ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047129-A2 | LATENT FLUORESCENT PROBES | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2008-04-24 | — | — | WO | disclosed |