Pantoprazole

Pantoprazole

SCHEMBL1649650

COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1OC.[H+].[NaH]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 14/20 0.52
ATP4B P51164 14/20 0.52
CYP2C9 P11712 2/20 0.52
KDM4E B2RXH2 1/20 0.52
SLC22A2 O15244 1/20 0.52
DDAH1 O94760 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
ABCB1 P08183 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ADRA1A P35348 1/20 0.52
FASN P49327 1/20 0.52
SLC47A2 Q86VL8 1/20 0.52
SLC47A1 Q96FL8 1/20 0.52
ABCG2 Q9UNQ0 1/20 0.52
ATP1A1 P05023 7/20 0.44
ATP1B1 P05026 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantoprazole SCHEMBL3542 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL5795111 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL4763505 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL1560742 0.99 ATP4A (0.53) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL27913225 0.98 ATP4A (0.52) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL1476428 0.98 ATP4A (0.52) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL1477291 0.98 ATP4A (0.52) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL21986309 0.98 ATP4A (0.52) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL7211409 0.98 ATP4A (0.52) ATP4AATP4BCYP2C9KDM4ESLC22A2
Pantoprazole SCHEMBL1476069 0.98 ATP4A (0.52) ATP4AATP4BCYP2C9KDM4ESLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130005200-A1 Methods of pulsed nuclear energy generation using piston-based systems Mayburd, Anatoly (US) 2013-01-03 US claimed
US-7148124-B1 Method for forming a fragile layer inside of a single crystalline substrate preferably for making silicon-on-insulator wafers USENKO ALEXANDER YURI 2006-12-12 US claimed
EP-0688849-B1 Fluorescent compounds NYCOMED AMERSHAM PLC (GB) 2000-01-12 EP claimed
EP-0556005-B1 Fluorescent compounds AMERSHAM INT PLC (GB) 1996-04-17 EP claimed
EP-0688849-A2 Fluorescent compounds AMERSHAM INTERNATIONAL plc (GB) 1995-12-27 EP claimed
US-5435937-A Fluorescent compounds AMERSHAM INTERNATIONAL PLC (GB) 1995-07-25 US claimed
EP-0556005-A1 Fluorescent compounds AMERSHAM INTERNATIONAL plc (GB) 1993-08-18 EP claimed
EP-4342892-A1 BRUTON'S TYROSINE KINASE AND MUTANT DEGRADER, COMPOSITION AND APPLICATION THEREOF Hangzhou Healzen Therapeutics Co., Ltd. (CN) 2024-03-27 EP disclosed
CN-108573321-B Method and system for optimizing quantities of radiopharmaceuticals to be produced 美国西门子医疗解决公司 2022-11-22 CN disclosed
CN-114558028-A Hydrogen molecule therapeutic agent for recovering brain function after TBI injury 北京工业大学 2022-05-31 CN disclosed
CN-111675724-B Luciferase substrate and preparation method and application thereof 山东大学 2021-09-21 CN disclosed
CN-113189260-A Hydrogen isotope on-line analysis micro-chromatography measurement and control system and control method thereof 中国工程物理研究院材料研究所 2021-07-30 CN disclosed
WO-2021011503-A1 MOSQUITO EGG CRYOPRESERVATION SANARIA INC. (US) 2021-01-21 WO disclosed
EP-0913448-A1 Fluorescent compound Nycomed Amersham PLC (GB) 1999-05-06 EP disclosed
US-5658494-A SOLID SCINTILLANT AMERSHAM INTERNATIONAL PLC (GB) 1997-08-19 US disclosed
EP-0744451-A1 Fluorescent compounds AMERSHAM INTERNATIONAL plc (GB) 1996-11-27 EP disclosed
EP-0556005-B1 Fluorescent compounds AMERSHAM INT PLC (GB) 1996-04-17 EP disclosed
EP-0688849-A2 Fluorescent compounds AMERSHAM INTERNATIONAL plc (GB) 1995-12-27 EP disclosed
US-5435937-A Fluorescent compounds AMERSHAM INTERNATIONAL PLC (GB) 1995-07-25 US disclosed
EP-0556005-A1 Fluorescent compounds AMERSHAM INTERNATIONAL plc (GB) 1993-08-18 EP disclosed