Bucricaine

Bucricaine

SCHEMBL1649809

CCCCNc1c2c(nc3ccccc13)CCCC2

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 10/20 0.82
ACHE P22303 9/20 0.82
APP P05067 2/20 0.82
BACE1 P56817 2/20 0.82
GABRP O00591 1/20 0.82
GABRD O14764 1/20 0.82
GABRA1 P14867 1/20 0.82
GABRB1 P18505 1/20 0.82
GABRG2 P18507 1/20 0.82
GABRB3 P28472 1/20 0.82
GABRA5 P31644 1/20 0.82
GABRA3 P34903 1/20 0.82
GABRA2 P47869 1/20 0.82
GABRB2 P47870 1/20 0.82
GABRA4 P48169 1/20 0.82
GABRE P78334 1/20 0.82
GABRA6 Q16445 1/20 0.82
GABRG1 Q8N1C3 1/20 0.82
GABRG3 Q99928 1/20 0.82
GABRQ Q9UN88 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8525172 0.96 BCHE (0.85) BCHEACHEAPPBACE1GABRP
SCHEMBL12552080 0.95 BCHE (0.88) BCHEACHEAPPBACE1GABRP
SCHEMBL7674463 0.95 BCHE (0.88) BCHEACHEAPPBACE1GABRP
SCHEMBL13480729 0.92 BCHE (0.92) BCHEACHEAPPBACE1GABRP
SCHEMBL24000133 0.92 BCHE (0.97) BCHEACHEAPPBACE1GABRP
SCHEMBL15168191 0.91 ACHE (1.00) BCHEACHEAPPBACE1GABRP
SCHEMBL29486236 0.91 ACHE (1.00) BCHEACHEAPPBACE1GABRP
SCHEMBL24164216 0.91 ACHE (1.00) BCHEACHEAPPBACE1GABRP
SCHEMBL12059555 0.91 ACHE (1.00) BCHEACHEAPPBACE1GABRP
Hydrochloric Acid SCHEMBL29711388 0.89 BCHE (1.00) BCHEACHEAPPBACE1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3111941-A1 COMPOSITIONS COMPRISING CHONDROITIN SULFATE FOR PROPHYLAXIS OR TREATMENT OF DAMAGED ARTICULAR CARTILAGE Patir, Süleyman (TR) 2017-01-04 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
US-20100191216-A1 INDICATIONS FOR LOCAL TRANSPORT OF ANAESTHETIC AGENTS BY ELECTROTRANSPORT DEVICES KEUSCH PRESTON 2010-07-29 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007041476-A2 INDICATIONS FOR LOCAL TRANSPORT OF ANAESTHETIC AGENTS BY ELECTROTRANSPORT DEVICES VYTERIS, INC. (US) 2007-04-12 WO claimed
US-20070078434-A1 Indications For Local Transport of Anaesthetic Agents By Electrotransport Devices VYTERIS, INC. (US) 2007-04-05 US claimed
EP-1696855-A1 DERMAL DRUG DELIVERY SYSTEM Medpharm Limited (GB) 2006-09-06 EP claimed
US-20060130266-A1 Dermal drug delivery system MEDPHARM LIMITED (GB) 2006-06-22 US claimed
EP-1586347-A1 Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability Vyteris, Inc. (US) 2005-10-19 EP claimed
US-20050228336-A1 Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability COLLATERAL AGENTS, LLC 2005-10-13 US claimed
WO-2005058226-A1 DERMAL DRUG DELIVERY SYSTEM MEDPHARM LIMITED (GB) 2005-06-30 WO claimed
EP-4603095-A2 IMPROVED PHARMACEUTICAL FORMULATIONS Ferring B.V. (NL) 2025-08-20 EP disclosed
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 WO disclosed
EP-0956026-A1 PHARMACEUTICAL PREPARATIONS COMPRISED OF SALTS OF HYALURONIC ACID WITH LOCAL ANAESTHETICS FIDIA S.p.A. (IT) 1999-11-17 EP disclosed
WO-1998017285-A1 PHARMACEUTICAL PREPARATIONS COMPRISED OF SALTS OF HYALURONIC ACID WITH LOCAL ANAESTHETICS FIDIA S.P.A. (IT) 1998-04-30 WO disclosed
US-5175172-A Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients DIETLIN FRANCOIS (FR) 1992-12-29 US disclosed