Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.85 |
| ▸ | ACHE | P22303 | 9/20 | 0.85 |
| ▸ | APP | P05067 | 2/20 | 0.85 |
| ▸ | BACE1 | P56817 | 2/20 | 0.85 |
| ▸ | GABRP | O00591 | 1/20 | 0.85 |
| ▸ | GABRD | O14764 | 1/20 | 0.85 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.85 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.85 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.85 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.85 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.85 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.85 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.85 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.85 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.85 |
| ▸ | GABRE | P78334 | 1/20 | 0.85 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.85 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.85 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.85 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674463 | 0.99 | BCHE (0.88) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL12552080 | 0.99 | BCHE (0.88) | BCHEACHEAPPBACE1GABRP | |
| Bucricaine SCHEMBL1649809 | 0.96 | BCHE (0.82) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL24000133 | 0.93 | BCHE (0.97) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL15168191 | 0.92 | ACHE (1.00) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL29486236 | 0.92 | ACHE (1.00) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL24164216 | 0.92 | ACHE (1.00) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL12059555 | 0.92 | ACHE (1.00) | BCHEACHEAPPBACE1GABRP | |
| Hydrochloric Acid SCHEMBL29711388 | 0.91 | BCHE (1.00) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL13480729 | 0.91 | BCHE (0.92) | BCHEACHEAPPBACE1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319429-B1 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI CHEM IND (JP) | 1994-04-27 | — | — | EP | claimed |
| US-4985430-A | ALZHEIMER*S DISEASE | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0319429-A2 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1989-06-07 | — | — | EP | claimed |
| JP-2152967-A | — | — | None | — | — | JP | disclosed |
| US-5861411-A | TREATING DISTURBANCES OF MEMORY SUCH AS SENILE DEMENTIA AND ALZHEIMER'S DISEASE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5536728-A | TREATMENT OF SENILE DEMENTIA AND ALZHEIMER'S DISEASE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0427636-B1 | 4-Acylaminopyridine derivatives | MITSUBISHI CHEM CORP (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5397785-A | Activators of cholinergic neurons to treat memory disorders such as senile dementia and Alzheimer's disease | MITSUBISHI KASEI CORPORATION (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0319429-B1 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI CHEM IND (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0319429-B1 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI CHEM IND (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |
| EP-0427636-A2 | 4-Acylaminopyridine derivatives | Mitsubishi Chemical Corporation (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4985430-A | ALZHEIMER*S DISEASE | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4985430-A | ALZHEIMER*S DISEASE | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4985430-A | ALZHEIMER*S DISEASE | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0394950-A1 | Pyridine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| JP-H02152967-A | 9-ACYLAMINO-TETRAHYDROACRIDINE DERIVATIVE AND AMELIORANT FOR DYSMNESIA CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORP | 1990-06-12 | — | — | JP | disclosed |
| EP-0319429-A2 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319429-A2 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319429-A2 | 9-Acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1989-06-07 | — | — | EP | disclosed |