Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498246 | 0.80 | ALDH1A1 (0.41) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16498310 | 0.79 | MME (0.43) | CTSSCTSKALDH1A1CAPN1ITGB1 | |
| SCHEMBL16498053 | 0.75 | ALDH1A1 (0.43) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16498054 | 0.75 | ALDH1A1 (0.43) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16498146 | 0.74 | ALDH1A1 (0.44) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16498150 | 0.74 | ALDH1A1 (0.44) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16510453 | 0.74 | ALDH1A1 (0.44) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16498330 | 0.74 | ALDH1A1 (0.44) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL16510451 | 0.71 | CTSS (0.64) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL31726300 | 0.70 | OPRD1 (0.44) | CTSLCTSSCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150500-A1 | CYCLIC AMINO ACID MOLECULES CONTAINING AZIRIDINE AMINO ACIDS AND METHODS OF PREPARING SAME | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2011-12-08 | — | — | WO | disclosed |