Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197007 | 0.88 | KMT2A (0.34) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL23120791 | 0.88 | KMT2A (0.38) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL3197011 | 0.88 | KMT2A (0.34) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL2340622 | 0.88 | KMT2A (0.38) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL15645461 | 0.86 | KMT2A (0.47) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL21624845 | 0.86 | KMT2A (0.33) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL23120812 | 0.86 | KMT2A (0.33) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL15760564 | 0.81 | OPRM1 (0.37) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL144836 | 0.81 | MEN1 (0.39) | KMT2AMEN1MAPK1GHSRGAA | |
| SCHEMBL391041 | 0.81 | KMT2A (0.43) | KMT2AKDM4EMEN1MAPK1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011049520-A1 | ADAMANTYL IMINOCARBONYL-SUBSTITUTED PYRIMIDINES AS INHIBITORS OF 1 1 BETAHSD1 | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |