Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197011 | 1.00 | KMT2A (0.34) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL23120812 | 0.92 | KMT2A (0.33) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL21624845 | 0.92 | KMT2A (0.33) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL1649897 | 0.88 | KMT2A (0.34) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL23120791 | 0.88 | KMT2A (0.38) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL2340622 | 0.88 | KMT2A (0.38) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL15760564 | 0.87 | OPRM1 (0.37) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL15645461 | 0.86 | KMT2A (0.47) | KMT2AKDM4EMEN1MAPK1GHSR | |
| SCHEMBL22962157 | 0.86 | MEN1 (0.32) | KMT2AMEN1MAPK1 | |
| SCHEMBL22962047 | 0.85 | TDP1 (0.33) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41149-E1 | Stereoisomerically pure 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid or a pharmaceutically acceptable salt thereof; antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-6031102-A | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| EP-0341493-B1 | Optically active pyridonecarboxylic acid derivatives | DAIICHI SEIYAKU CO (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5767127-A | BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5587386-A | BACTERICIDES, MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |