Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335445 | 0.88 | FFAR1 (0.63) | CYP4F2CYP4A11NPC1RAB9AMAPT | |
| SCHEMBL16511748 | 0.86 | LTB4R (0.57) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| SCHEMBL112488 | 0.83 | CYP4F2 (0.66) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| SCHEMBL15522740 | 0.82 | CYP4F2 (0.66) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| SCHEMBL7646563 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27517466 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| SCHEMBL27624350 | 0.82 | ESR1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTFFAR1 | |
| SCHEMBL2633187 | 0.81 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| SCHEMBL10076459 | 0.81 | ALDH1A1 (0.55) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A | |
| SCHEMBL2628190 | 0.81 | SMN1; SMN2 (0.59) | CYP4F2CYP4A11ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154678-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011154678-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |