Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499387 | 0.80 | HDAC4 (0.34) | — | |
| SCHEMBL16499338 | 0.75 | CES2 (0.36) | — | |
| SCHEMBL12813285 | 0.73 | GAA (0.38) | GAAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL16499576 | 0.72 | CES2 (0.36) | HSD11B1 | |
| SCHEMBL16499519 | 0.71 | SLC6A2 (0.35) | GAAIDO1TDO2 | |
| SCHEMBL12813234 | 0.71 | ALDH1A1 (0.33) | OPRM1OPRD1OPRK1OPRL1IDO1 | |
| SCHEMBL598722 | 0.70 | GAA (0.57) | GAAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL16499266 | 0.69 | ALDH1A1 (0.43) | GAAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL16499484 | 0.68 | CES2 (0.35) | HSD11B1 | |
| SCHEMBL16499492 | 0.68 | AR (0.34) | GAAOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |