Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499266 | 0.82 | ALDH1A1 (0.43) | SLC6A2SLC6A4AOC3SLC6A3GAA | |
| SCHEMBL16499484 | 0.81 | CES2 (0.35) | — | |
| SCHEMBL16499492 | 0.81 | AR (0.34) | BRD4GAA | |
| SCHEMBL16499338 | 0.73 | CES2 (0.36) | — | |
| SCHEMBL12813412 | 0.72 | SLC6A2 (0.35) | SLC6A2SLC6A4BRD4AOC3ADRB2 | |
| SCHEMBL16499250 | 0.72 | CYP11B1 (0.37) | ADRB2 | |
| SCHEMBL16499247 | 0.71 | GAA (0.38) | GAAIDO1TDO2 | |
| SCHEMBL16499193 | 0.70 | ALDH1A1 (0.32) | SLC6A2AOC3 | |
| SCHEMBL14879778 | 0.67 | — | — | |
| SCHEMBL1426754 | 0.66 | TSHR (0.50) | BRD4AOC3ADRB2HPGDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |