Ribostamycin

Ribostamycin

SCHEMBL1649929

NC[C@H]1O[C@H](O[C@H]2[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](N)C[C@@H]2N)[C@H](N)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
TSHR P16473 2/20 0.91
HSD17B10 Q99714 1/20 0.91
LRAT O95237 2/20 0.88
MEN1 O00255 2/20 0.88
TRPV1 Q8NER1 1/20 0.88
BLM P54132 1/20 0.81
RECQL P46063 1/20 0.81
TDP1 Q9NUW8 1/20 0.81
KDM4E B2RXH2 1/20 0.78
ALOX15 P16050 1/20 0.78
GJA1 P17302 1/20 0.72
GJB2 P29033 1/20 0.72
CYP2C9 P11712 1/20 0.72
KMT2A Q03164 1/20 0.72
ALDH1A1 P00352 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribostamycin SCHEMBL48820 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL13599669 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL19944115 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL13605470 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL15432715 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL19619289 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL19619262 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL17321247 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
SCHEMBL16882157 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1
Ribostamycin SCHEMBL20530016 1.00 LMNA (1.00) LMNATSHRHSD17B10LRATMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4331675-B1 SYSTEMS FOR TREATING PULMONARY INFECTIONS INSMED INC (US) 2026-01-28 EP claimed
EP-3675865-B1 CRYSTALLINE FORMS OF COMPOUNDS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH UNIV WASHINGTON (US) 2025-04-02 EP claimed
CN-118695873-A Pharmaceutical composition comprising human hyaluronidase PH20 and a drug 阿特根公司 2024-09-24 CN claimed
EP-4005576-B1 SYSTEMS FOR TREATING PULMONARY INFECTIONS INSMED INC (US) 2023-12-13 EP claimed
EP-3122757-B1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO LTD (CN) 2023-09-06 EP claimed
EP-2600868-B1 COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND AN AMINOGLYCODISE ANTIMICROBIAL AGENT HELPERBY THERAPEUTICS LTD (GB) 2022-03-09 EP claimed
CN-111410899-B Photocureable coating and preparation method and application thereof 浙江伟星实业发展股份有限公司 2022-03-01 CN claimed
US-20200165572-A1 ENGINEERED SUBSTRATES FOR HIGH-THROUGHPUT GENERATION OF 3D MODELS OF TUMOR DORMANCY, RELAPSE AND MICROMETASTASES FOR PHENOTYPE SPECIFIC DRUG DISCOVERY AND DEVELOPMENT ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-05-28 US claimed
CN-106554374-B A method of purification prepares vistamycin from ribostamycin fermentation liquid 无锡福祈制药有限公司 2018-11-27 CN claimed
CN-106667901-A Ribostamycin sulfate injection and preparation method thereof 无锡福祈制药有限公司 2017-05-17 CN claimed
CN-103536554-A Ribostamycin sulfate composition freeze-dried powder for injection HAINAN WEIKANG PHARM QIANSHAN 2014-01-29 CN claimed
CN-103393543-A Method using 3D printing technology to prepare dropping pills WEI XUEWEN 2013-11-20 CN claimed
CN-101380291-A Sustained-release injection and preparation method thereof QINGZHONG KONG (CN) 2009-03-11 CN claimed
CN-101380292-A Sustained-released injection and preparation method and use thereof QINGZHONG KONG (CN) 2009-03-11 CN claimed
CN-1923167-A Sustained-release injection and preparation method and application thereof KONG QINGZHONG (CN) 2007-03-07 CN claimed
CN-1449743-A Medicinal aerosol and preparation process thereof WANG SHILI (CN) 2003-10-22 CN claimed
CN-1435257-A Epidermal mucosa disinfectant contg. recombinant human epidermal growth factor ZHAO BAORUI (CN) 2003-08-13 CN claimed
CN-1069192-C Aerosol preparation and preparation method thereof WANG SHILI (CN) 2001-08-08 CN claimed
CN-1209320-A Medicine WANG SHILI (CN) 1999-03-03 CN claimed
CN-1123141-A Aerosol preparation and preparation method thereof WANG SHILI (CN) 1996-05-29 CN claimed