⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182010 | 0.79 | CES2 (0.71) | — | |
| SCHEMBL1066873 | 0.79 | CES2 (1.00) | — | |
| SCHEMBL11773764 | 0.78 | CES2 (0.56) | — | |
| Thiophene Carboxylic Acid SCHEMBL27774764 | 0.77 | DAO (1.00) | — | |
| SCHEMBL225933 | 0.77 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL7062244 | 0.77 | DAO (1.00) | — | |
| Thiophene Carboxylic Acid SCHEMBL83000 | 0.77 | — | — | |
| SCHEMBL25149651 | 0.75 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL1814 | 0.75 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL5287669 | 0.75 | DAO (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296092-A | Mucolytic benzene and thiophene-carbothioic acid 2-aminoalkyl ester acid salts | A. H. ROBINS COMPANY, INC. (US) | 1981-10-20 | — | — | US | claimed |
| US-4252952-A | 7-(α-Substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids and their derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | claimed |
| CN-112512529-B | Cyclopentenepurine derivative or salt thereof | 富士胶片株式会社 | 2024-06-18 | — | — | CN | disclosed |
| EP-3831388-B1 | CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FOR USE IN SUPPRESSING ADENOVIRUS | FUJIFILM CORP (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-3831836-B1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-115974758-A | Carboxymethyl ketone compound and preparation method thereof | 生物岛实验室 | 2023-04-18 | — | — | CN | disclosed |
| EP-3831388-A1 | CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3831836-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-20210155644-A1 | CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2021-05-27 | — | — | US | disclosed |
| US-20210147456-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2021-05-20 | — | — | US | disclosed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| US-4994571-A | Reacting heterocycle-containing sulfonamide compound with carbonyl compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0305939-A1 | Process of producing sulfonylurea derivatives | Takeda Chemical Industries, Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4363920-A | Process for the preparation of N-[2-(-thenoyl)thiopropionyl]-glycine | B.T.B. INDUSTRIA CHIMICA S.P.A. (IT) | 1982-12-14 | — | — | US | disclosed |
| US-4296092-A | Mucolytic benzene and thiophene-carbothioic acid 2-aminoalkyl ester acid salts | A. H. ROBINS COMPANY, INC. (US) | 1981-10-20 | — | — | US | disclosed |
| US-4210666-A | Mucolytic thiophenecarboxamido alkyl mercaptans | A. H. ROBINS COMPANY, INC. (US) | 1980-07-01 | — | — | US | disclosed |
| US-4039677-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-02 | — | — | US | disclosed |