Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.35 |
| ▸ | ATG7 | O95352 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253963 | 0.88 | DNPH1 (0.41) | — | |
| SCHEMBL12253777 | 0.85 | ADORA2A (0.47) | ADORA2APRMT5WDR77 | |
| SCHEMBL13392121 | 0.85 | ADORA2A (0.47) | ADORA2APRMT5WDR77 | |
| SCHEMBL12254003 | 0.84 | P2RY2 (0.45) | — | |
| SCHEMBL12306916 | 0.80 | PRMT5 (0.33) | ADORA2APRMT5WDR77STING1 | |
| SCHEMBL12253960 | 0.77 | FAP (0.37) | ATG7STING1 | |
| SCHEMBL12305472 | 0.77 | FAP (0.36) | — | |
| SCHEMBL15682898 | 0.76 | P2RX1 (0.46) | — | |
| SCHEMBL15682919 | 0.76 | ADORA2A (0.41) | ADORA2A | |
| SCHEMBL16502871 | 0.75 | ADK (0.35) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280973-B1 | CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2012-11-28 | — | — | EP | disclosed |