Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 11/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190171 | 0.92 | CYP26A1 (0.37) | CYP26A1POLBGAANPSR1KMT2A | |
| SCHEMBL13190170 | 0.90 | CNR1 (0.37) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6049430 | 0.75 | KCNN4 (0.42) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16503515 | 0.74 | CYP26A1 (0.47) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11914197 | 0.66 | ALDH1A1 (0.46) | CYP3A4PTPN1KMT2AKDM4EMAPT | |
| SCHEMBL16284309 | 0.64 | PTGS2 (0.42) | CYP1A2CYP2C9CYP2C19KMT2AKDM4E | |
| SCHEMBL17694473 | 0.64 | AKR1C3 (0.54) | CYP1A2CYP2C19KMT2AKDM4E | |
| SCHEMBL17694465 | 0.64 | AKR1C3 (0.54) | CYP1A2CYP2C19KMT2AKDM4E | |
| SCHEMBL15695556 | 0.64 | PTGS2 (0.42) | CYP1A2CYP2C9CYP2C19KMT2AKDM4E | |
| SCHEMBL17694468 | 0.64 | AKR1C3 (0.54) | CYP1A2CYP2C19KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079869-B2 | Chiral disulfonimides | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-20110313150-A1 | CHIRAL DISULFONIMIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313150-A1 | CHIRAL DISULFONIMIDES | STS, SUDS3, SF1 | CYP26A1 634/4885CYP3A4 873/4885CYP1A2 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.