Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16503511 | 0.92 | CYP26A1 (0.37) | CYP26A1KMT2AGAAKDM4ENPSR1 | |
| SCHEMBL13190170 | 0.84 | CNR1 (0.37) | CYP26A1 | |
| SCHEMBL6049430 | 0.79 | KCNN4 (0.42) | CYP26A1KMT2AALDH1A1 | |
| SCHEMBL16503515 | 0.78 | CYP26A1 (0.47) | CYP26A1 | |
| SCHEMBL11071476 | 0.67 | DGAT1 (0.34) | — | |
| SCHEMBL4720153 | 0.66 | ACP3 (0.39) | KMT2AALDH1A1STAT1TNF | |
| SCHEMBL11074828 | 0.64 | DGAT1 (0.32) | — | |
| SCHEMBL11076796 | 0.64 | L3MBTL1 (0.39) | KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9709122 | 0.64 | ALDH1A1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL1818480 | 0.63 | ALDH1A1 (0.58) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403842-B1 | CHIRAL DISULFONIMIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2016-06-29 | — | — | EP | disclosed |
| WO-2010099786-A1 | CHIRAL DISULFONIMIDES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2010-09-10 | — | — | WO | disclosed |