Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918714 | 0.87 | MEN1 (0.42) | PDE10AMEN1KMT2ALMNAMAPT | |
| SCHEMBL7916811 | 0.83 | CCNT1 (0.40) | PDE10ACCNT1CDK9MEN1KMT2A | |
| SCHEMBL16509513 | 0.83 | ALOX15 (0.52) | PDE10AMEN1KMT2ALMNAMAPT | |
| SCHEMBL7916046 | 0.79 | HTR5A (0.39) | PDE10ACCNT1CDK9MEN1KMT2A | |
| SCHEMBL16509516 | 0.79 | HTR5A (0.52) | LMNAMAPT | |
| SCHEMBL16503496 | 0.76 | HTR2C (0.43) | PDE10ALMNAMAPTALDH1A1KDM4E | |
| SCHEMBL16503575 | 0.72 | GABRG2 (0.35) | — | |
| SCHEMBL16502693 | 0.70 | CSNK2A2 (0.45) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16502677 | 0.70 | ALOX15 (0.53) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7916646 | 0.69 | DHODH (0.48) | PDE10AKDM4ERAB9AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394987-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2011-12-14 | — | — | EP | disclosed |