SCHEMBL16503752

SCHEMBL16503752

Cc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cnc(Cn2nnc(C(F)(F)F)n2)nc1-c1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 19/20 0.41
▸ SLC2A3 P11169 19/20 0.41
▸ SLC2A4 P14672 19/20 0.41
▸ SLC2A2 P11168 8/20 0.39
▸ EPAS1 Q99814 1/20 0.39
▸ ADORA3 P0DMS8 1/20 0.36
▸ HRH2 P25021 1/20 0.36
▸ HRH1 P35367 1/20 0.36
▸ PTGER4 P35408 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16503751 0.93 EPAS1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2EPAS1
SCHEMBL16503749 0.92 EPAS1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2EPAS1
SCHEMBL16503738 0.92 EPAS1 (0.44) SLC2A1SLC2A3SLC2A4SLC2A2EPAS1
SCHEMBL16503763 0.91 EPAS1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2EPAS1
SCHEMBL16572256 0.87 EPAS1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2EPAS1
SCHEMBL1696948 0.85 EPAS1 (0.42) EPAS1
SCHEMBL16503753 0.83 EPAS1 (0.41) EPAS1
SCHEMBL16503748 0.83 EPAS1 (0.41) EPAS1
SCHEMBL18828875 0.80 EPAS1 (0.39) SLC2A1SLC2A3SLC2A4SLC2A2EPAS1
SCHEMBL13085372 0.79 SLC2A1 (0.39) SLC2A1SLC2A3SLC2A4SLC2A2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8980886-B2 Anthranilic acid derivatives BAYER CROPSCIENCE AG (DE) 2015-03-17 — — US disclosed
US-8980886-B2 Anthranilic acid derivatives BAYER CROPSCIENCE AG (DE) 2015-03-17 — — US disclosed
US-20110312953-A1 ANTHRANILIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-12-22 — — US disclosed
US-20110312953-A1 ANTHRANILIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2011-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312953-A1 ANTHRANILIC ACID DERIVATIVES ANTXR2, NQO2, ACLY SLC2A1 4190/4885SLC2A3 4342/4885SLC2A4 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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