Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 7/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637205 | 0.84 | DPP4 (0.41) | DPP8DPP4DPP9DPP7ENPEP | |
| SCHEMBL9637204 | 0.84 | DPP4 (0.41) | DPP8DPP4DPP9DPP7ENPEP | |
| SCHEMBL3060526 | 0.82 | DPP8 (0.42) | DPP8DPP4DPP9DPP7 | |
| SCHEMBL2197913 | 0.81 | DPP4 (0.48) | DPP8DPP4DPP9BMP1ENPEP | |
| SCHEMBL3422273 | 0.80 | ENPEP (0.46) | NOD1TASP1ENPEPCASP1CASP3 | |
| SCHEMBL3422282 | 0.80 | ENPEP (0.46) | NOD1TASP1ENPEPCASP1CASP3 | |
| SCHEMBL2185034 | 0.78 | TASP1 (0.42) | DPP8DPP4DPP9TASP1ENPEP | |
| SCHEMBL2503880 | 0.77 | NOD1 (0.57) | NOD1DPP8DPP4DPP9BMP1 | |
| SCHEMBL2503883 | 0.77 | NOD1 (0.57) | NOD1DPP8DPP4DPP9BMP1 | |
| SCHEMBL9637243 | 0.75 | ACE (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |