Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 9/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15232376 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL15242584 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL16521856 | 0.90 | CYP3A4 (0.44) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL16506084 | 0.86 | KCNA5 (0.49) | SMN1; SMN2TSHRCYP3A4LMNAMAPK1 | |
| SCHEMBL16506129 | 0.86 | CYP3A4 (0.51) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL16505815 | 0.86 | CYP3A4 (0.42) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL16506356 | 0.86 | CYP3A4 (0.49) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL16521842 | 0.84 | CYP3A4 (0.47) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL15232461 | 0.83 | TSHR (0.53) | SMN1; SMN2TSHRCYP3A4LMNAMAPT | |
| SCHEMBL17722013 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCYP3A4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328061-B2 | Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols | TRUSTEES OF BOSTON COLLEGE (US) | 2016-05-03 | — | — | US | disclosed |
| US-9328061-B2 | Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols | TRUSTEES OF BOSTON COLLEGE (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150057451-A1 | SIMPLE ORGANIC MOLECULES AS CATALYSTS FOR PRACTICAL AND EFFICIENT ENANTIOSELECTIVE SYNTHESIS OF AMINES AND ALCOHOLS | NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT | 2015-02-26 | — | — | US | disclosed |
| US-20150057451-A1 | SIMPLE ORGANIC MOLECULES AS CATALYSTS FOR PRACTICAL AND EFFICIENT ENANTIOSELECTIVE SYNTHESIS OF AMINES AND ALCOHOLS | NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT | 2015-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057451-A1 | SIMPLE ORGANIC MOLECULES AS CATALYSTS FOR PRACTICAL AND EFFICIENT ENANTIOSELECTIVE SYNTHESIS OF AMINES AND ALCOHOLS | ADH1C, ADH5, ADH1A | SMN1; SMN2 3486/4885TSHR 1559/4885CYP3A4 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.