Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16506928 | 0.80 | CHRM2 (0.57) | CHRM2CHRM1OPRM1SMN1; SMN2SLC6A4 | |
| SCHEMBL16507502 | 0.77 | CHRM2 (0.60) | CHRM2CHRM1OPRM1SMN1; SMN2SLC6A4 | |
| Hydrochloric Acid SCHEMBL16507309 | 0.76 | CHRM2 (0.58) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL7382485 | 0.76 | SLC6A3 (0.43) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL7047849 | 0.74 | SLC6A3 (0.47) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL16506943 | 0.74 | SLC6A3 (0.55) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL3517260 | 0.73 | CHRM2 (0.54) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL16521037 | 0.73 | SLC6A3 (0.45) | CHRM2CHRM1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2023 | 0.72 | OPRM1 (0.48) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL7366120 | 0.72 | CHRM2 (0.49) | CHRM2CHRM1OPRM1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150057443-A1 | Cycloalkyl Amine Compounds | PREXA PHARMACEUTICALS, INC. | 2015-02-26 | — | — | US | disclosed |
| WO-2015027058-A2 | CYCLOLKYL AMINE COMPOUNDS | PREXA PHARMACEUTICALS, INC. (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20150057443-A1 | Cycloalkyl Amine Compounds | PREXA PHARMACEUTICALS, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20150057443-A1 | Cycloalkyl Amine Compounds | PREXA PHARMACEUTICALS, INC. | 2015-02-26 | — | — | US | disclosed |
| WO-2015027058-A2 | CYCLOLKYL AMINE COMPOUNDS | PREXA PHARMACEUTICALS, INC. (US) | 2015-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057443-A1 | Cycloalkyl Amine Compounds | HCRTR2, HCRTR1, HTR2C | CHRM2 10/4885CHRM1 34/4885CA12 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.