SCHEMBL16507915

SCHEMBL16507915

CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NPBWR1 P48145 18/20 0.66
▸ GLP1R P43220 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13363679 0.94 NPBWR1 (0.69) NPBWR1GLP1R
SCHEMBL13363682 0.91 GLP1R (0.69) NPBWR1GLP1R
SCHEMBL16508101 0.84 IL23R (0.66) NPBWR1GLP1R
SCHEMBL16507895 0.84 IL23R (0.63) NPBWR1
SCHEMBL21191024 0.84 NPBWR1 (0.61) NPBWR1
SCHEMBL16507967 0.83 IL23R (0.65) NPBWR1GLP1R
SCHEMBL30211346 0.83 KISS1R (0.63) NPBWR1
SCHEMBL16507822 0.83 MMP2 (0.54) GLP1R
SCHEMBL21191025 0.83 NPBWR1 (0.60) NPBWR1
SCHEMBL26080241 0.82 GLP1R (0.68) NPBWR1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPBWR1 730/4885GLP1R 120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback