SCHEMBL16507945

SCHEMBL16507945

CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)NC)[C@@H](C)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.50
▸ GLP1R P43220 8/20 0.49
▸ SCTR P47872 1/20 0.49
▸ NPY5R Q15761 4/20 0.48
▸ NPY1R P25929 3/20 0.48
▸ NPY4R P50391 3/20 0.48
▸ NPY2R P49146 1/20 0.48
▸ RAMP3 O60896 5/20 0.47
▸ CALCR P30988 5/20 0.47
▸ OPRM1 P35372 1/20 0.46
▸ OPRD1 P41143 1/20 0.46
▸ OPRK1 P41145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507764 0.92 NPY4R (0.54) APLNRNPY5RNPY1RNPY4RNPY2R
SCHEMBL16507848 0.90 APLNR (0.50) APLNRGLP1RSCTRNPY5RNPY1R
SCHEMBL16508056 0.90 GLP1R (0.56) APLNRGLP1RSCTRNPY5RNPY1R
SCHEMBL16507845 0.89 NPY4R (0.58) APLNRGLP1RSCTRNPY5RNPY1R
SCHEMBL16508501 0.89 NPY4R (0.57) APLNRNPY5RNPY1RNPY4RNPY2R
SCHEMBL16508473 0.88 NPY5R (0.45) APLNRGLP1RSCTRNPY5RNPY1R
SCHEMBL16507752 0.87 NPY5R (0.60) APLNRGLP1RSCTRNPY5RNPY1R
SCHEMBL16508549 0.86 APLNR (0.48) APLNRGLP1RSCTRNPY5RNPY1R
SCHEMBL16508567 0.86 NPY4R (0.54) APLNRNPY5RNPY1RNPY4RNPY2R
SCHEMBL16508576 0.85 NPY4R (0.52) APLNRGLP1RNPY5RNPY1RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR APLNR 222/4885GLP1R 120/4885SCTR 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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