Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 5/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CALCR | P30988 | 3/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | GIPR | P48546 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | GRPR | P30550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16507916 | 0.99 | APLNR (0.52) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507936 | 0.96 | GLP1R (0.50) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507946 | 0.96 | GLP1R (0.50) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507912 | 0.95 | APLNR (0.52) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507962 | 0.95 | APLNR (0.52) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507825 | 0.93 | APLNR (0.53) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507834 | 0.93 | GLP1R (0.50) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507772 | 0.90 | APLNR (0.51) | APLNRBACE1GLP1RCRHR1CRHR2 | |
| SCHEMBL16507773 | 0.89 | OPRM1 (0.49) | APLNRGLP1RF2PSMB5 | |
| SCHEMBL16508044 | 0.87 | PSMB5 (0.49) | APLNRGLP1RF2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | ANTHOR THERAPEUTICS, INC. | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294738-A1 | PTHR1 RECEPTOR COMPOUNDS | PTH1R, MC1R, CASR | APLNR 222/4885BACE1 132/4885GLP1R 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.