SCHEMBL16507773

SCHEMBL16507773

CCCCCCCCCCCCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(C)=O)[C@@H](C)CC

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 1/20 0.49
▸ OPRD1 P41143 1/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ F2 P00734 4/20 0.49
▸ GLP1R P43220 8/20 0.48
▸ KISS1R Q969F8 2/20 0.47
▸ PSMB5 P28074 2/20 0.46
▸ APLNR P35414 1/20 0.45
▸ NPY1R P25929 1/20 0.43
▸ NPY2R P49146 1/20 0.43
▸ NPY4R P50391 1/20 0.43
▸ NPY5R Q15761 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507936 0.92 GLP1R (0.50) F2GLP1RAPLNR
SCHEMBL16507946 0.92 GLP1R (0.50) F2GLP1RAPLNR
SCHEMBL16508102 0.91 F2 (0.46) OPRM1OPRD1OPRK1F2GLP1R
SCHEMBL16508044 0.91 PSMB5 (0.49) F2GLP1RPSMB5APLNR
SCHEMBL16507751 0.91 NPY5R (0.47) OPRM1OPRD1OPRK1F2GLP1R
SCHEMBL16507772 0.90 APLNR (0.51) OPRM1OPRD1OPRK1F2GLP1R
SCHEMBL16508053 0.89 APLNR (0.52) F2GLP1RPSMB5APLNR
SCHEMBL16507916 0.88 APLNR (0.52) F2GLP1RPSMB5APLNR
SCHEMBL16507834 0.88 GLP1R (0.50) F2GLP1RAPLNR
SCHEMBL16508132 0.86 NPY5R (0.48) OPRM1OPRD1OPRK1F2KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR OPRM1 1747/4885OPRD1 1000/4885OPRK1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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