Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508380 | 0.85 | TSHR (0.52) | MYCLTB4R2POLBTSHRALDH1A1 | |
| SCHEMBL16508384 | 0.82 | TP53 (0.44) | MYCLTB4R2POLBTSHRALDH1A1 | |
| SCHEMBL15492964 | 0.75 | ADRA2C (0.54) | LTB4R2POLBTSHRNPC1ALDH1A1 | |
| SCHEMBL27922019 | 0.72 | TSHR (0.49) | MYCPOLBNR4A1TSHRNPC1 | |
| SCHEMBL5167543 | 0.71 | IDO1 (0.47) | MYCNR4A1TSHRNR1I2CYP2C9 | |
| SCHEMBL7635322 | 0.70 | ALDH1A1 (0.43) | POLBTSHRNR1I2CYP2C9IDO1 | |
| SCHEMBL1803233 | 0.69 | TSHR (0.54) | LTB4R2POLBTSHRALDH1A1AKR1C3 | |
| SCHEMBL8174284 | 0.69 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL2425674 | 0.69 | ALDH1A1 (0.53) | MYCPOLBTSHRNPC1RAB9A | |
| SCHEMBL1004360 | 0.69 | MLYCD (0.62) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464060-B2 | Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20150057298-A1 | NOVEL COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2015-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057298-A1 | NOVEL COMPOUNDS | F12, C1R, CHRM1 | MYC 4275/4885LTB4R2 325/4885POLB 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.