Lauroguadine

Lauroguadine

SCHEMBL1651264

CCCCCCCCCCCCOc1ccc(N=C(N)N)cc1N=C(N)N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 1.00
DAPK3 O43293 1/20 1.00
JAK2 O60674 1/20 1.00
ROCK2 O75116 1/20 1.00
PRKCG P05129 1/20 1.00
CDK1 P06493 1/20 1.00
PIM1 P11309 1/20 1.00
RPS6KB1 P23443 1/20 1.00
CDK2 P24941 1/20 1.00
AKT1 P31749 1/20 1.00
AKT2 P31751 1/20 1.00
MAPKAPK2 P49137 1/20 1.00
BLK P51451 1/20 1.00
RPS6KA3 P51812 1/20 1.00
JAK3 P52333 1/20 1.00
LIMK1 P53667 1/20 1.00
PRKCZ Q05513 1/20 1.00
PRKCD Q05655 1/20 1.00
PAK1 Q13153 1/20 1.00
STK3 Q13188 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lauroguadine SCHEMBL21494449 0.99 CHUK (0.97) CHUKDAPK3JAK2ROCK2PRKCG
Lauroguadine SCHEMBL28331072 0.97 CHUK (0.95) CHUKDAPK3JAK2ROCK2PRKCG
Hydrochloric Acid SCHEMBL28332581 0.75 CHUK (0.60) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL27663840 0.75 FURIN (0.77) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL5243029 0.69 HTR3E (1.00) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL8611330 0.69 SMPD1 (0.57) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL22521646 0.69 SMPD1 (0.57) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL16201871 0.68 CHUK (0.51) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL29510772 0.68 CHUK (0.51) CHUKDAPK3JAK2ROCK2PRKCG
SCHEMBL908852 0.68 CHUK (0.51) CHUKDAPK3JAK2ROCK2PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116998495-A Antibacterial agent for aluminum alloy and preparation method thereof 山东创新金属科技有限公司 2023-11-07 CN disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed