Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28792817 | 0.71 | ESR2 (0.74) | ESR2NPSR1GAASMN1; SMN2NPC1 | |
| SCHEMBL16512869 | 0.67 | ESR2 (0.46) | ESR2NPSR1GAASMN1; SMN2NPC1 | |
| SCHEMBL1407223 | 0.61 | NR1H2 (0.49) | ESR2NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1094058 | 0.61 | ESR2 (0.75) | ESR2NPSR1GAASMN1; SMN2NPC1 | |
| SCHEMBL31670573 | 0.60 | ESR2 (0.67) | ESR2GAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31691548 | 0.60 | ESR2 (0.46) | ESR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9910895 | 0.60 | ESR2 (0.50) | ESR2GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11730545 | 0.60 | RAB9A (0.42) | ESR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL13602488 | 0.60 | SMN1; SMN2 (0.57) | NPSR1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4876232 | 0.60 | RORC (0.46) | NPSR1GAAALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |