Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28792817 | 0.76 | ESR2 (0.74) | ESR2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL29501081 | 0.71 | IRAK4 (0.39) | KDM4EMAPT | |
| SCHEMBL11730545 | 0.71 | RAB9A (0.42) | ESR2KDM4EADORA3MAPTNPC1 | |
| SCHEMBL16512870 | 0.69 | BCAT1 (0.41) | ESR2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL16499203 | 0.69 | L3MBTL1 (0.46) | ESR2KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL1638692 | 0.69 | ALOX15 (0.42) | KDM4ERAB9ASMN1; SMN2GAALMNA | |
| SCHEMBL31691548 | 0.68 | ESR2 (0.46) | ESR2KDM4EMAPTNPC1RAB9A | |
| SCHEMBL16512864 | 0.67 | ESR2 (0.42) | ESR2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20413677 | 0.67 | L3MBTL1 (0.56) | KDM4ESMN1; SMN2LDHAALDH1A1MAPK1 | |
| SCHEMBL1747314 | 0.67 | KDM4E (0.47) | KDM4EADORA3MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |