Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856649 | 0.91 | TBXA2R (0.50) | TBXA2RPTGDRPTGDR2MAPTKDM4E | |
| SCHEMBL6878036 | 0.90 | PTGDR2 (0.65) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL27655904 | 0.87 | TBXA2R (0.48) | TBXA2RPTGDRPTGDR2MAPTKDM4E | |
| SCHEMBL525025 | 0.82 | TBXA2R (0.71) | TBXA2RPTGDRPTGDR2RAB9ANPC1 | |
| SCHEMBL1652154 | 0.82 | PTGDR2 (0.69) | TBXA2RPTGDRPTGDR2ALDH1A1MAPT | |
| SCHEMBL1651004 | 0.79 | TBXA2R (0.48) | TBXA2RPTGDRPTGDR2ALDH1A1MAPT | |
| SCHEMBL27634902 | 0.79 | POLB (0.44) | TBXA2RPTGDRPTGDR2ALDH1A1MAPT | |
| SCHEMBL6016956 | 0.79 | DHPS (0.37) | TBXA2RPTGDRPTGDR2ALDH1A1MAPT | |
| SCHEMBL27634905 | 0.79 | PTGDR2 (0.65) | TBXA2RPTGDRPTGDR2 | |
| SCHEMBL1652081 | 0.78 | GLA (0.43) | TBXA2RPTGDRPTGDR2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4671955-B2 | — | — | 2011-04-20 | — | — | JP | claimed |
| JP-2006524645-A | — | — | 2006-11-02 | — | — | JP | claimed |
| EP-1633726-A1 | PYRIMIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES MEDIATED BY CRTH2 | Actimis Pharmaceuticals, Inc., (US) | 2006-03-15 | — | — | EP | claimed |
| WO-2004096777-A1 | PYRIMIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES MEDIATED BY CRTH2 | ACTIMIS PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | WO | claimed |