Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | BCKDK | O14874 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16527407 | 0.92 | KDM4E (0.67) | KDM4EMIFMAOAMAOBMAPT | |
| SCHEMBL24343672 | 0.86 | BCKDK (0.45) | KDM4EBCKDKMCL1RXFP1MIF | |
| SCHEMBL20593399 | 0.84 | MAOA (0.49) | KDM4EMAOAMAOBMAPTALDH1A1 | |
| SCHEMBL24343663 | 0.81 | KDM4E (0.50) | KDM4EMIFMAPTALDH1A1HPGD | |
| SCHEMBL4922476 | 0.81 | BCKDK (0.49) | KDM4EBCKDKMCL1RXFP1MIF | |
| SCHEMBL11574923 | 0.81 | KDM4E (0.61) | KDM4EBCKDKMCL1RXFP1MIF | |
| SCHEMBL12748045 | 0.81 | KDM4E (0.61) | KDM4EBCKDKMCL1RXFP1MAPT | |
| SCHEMBL6558940 | 0.81 | KDM4E (0.61) | KDM4EBCKDKMCL1RXFP1MIF | |
| SCHEMBL15003270 | 0.80 | MAOA (0.49) | KDM4EMIFMAOAMAOBMAPT | |
| SCHEMBL6070119 | 0.80 | KDM4E (0.81) | KDM4EMAPTALDH1A1HCRTR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842937-B1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-2842937-B1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| EP-2842937-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | HLA-B, HLA-A, HLA-C | KDM4E 1302/4885BCKDK 1206/4885MCL1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.