Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055644 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL16747704 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL24369271 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL16451555 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL11987178 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL12227907 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL18751241 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL4738149 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL22754540 | 0.82 | MEN1 (0.49) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E | |
| SCHEMBL24369272 | 0.82 | KDM4E (0.51) | SMN1; SMN2PSMB1PSMB5PSMB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058399-A1 | Branched polymer, method for making the same, and applications thereof | NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY (TW) | 2012-03-08 | — | — | US | disclosed |
| US-20120058399-A1 | Branched polymer, method for making the same, and applications thereof | NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY (TW) | 2012-03-08 | — | — | US | disclosed |